PAPERS

Nakanoh, S.^‡, Stamataki S.^‡, Garcia-Perez B., Azzi C., Carr H.L, PokhilkoA, Yu L., Doshi L., Boezio L.M., Melchionda M., Howell S, Skehel M., Oxley D., Andrews S., BriscoeJ. *, Rayon T.* (2025). Protein degradation shapes developmental tempo in mouse and human neural progenitors. *co-corresponding author, ^‡equal contribution. bioRxiv https://doi.org/10.1101/2024.08.01.604391
Iyer D.P., Khoei H.H., van der Weijden V.A., Kagawa H, Pradhan SJ, McCarthy A., Rayon T., Simon C.S., Dunkel I., Wamaitha S.E, Elder K., Snell P., Christie L., Schulz E.G., Niakan K. K., Rivron N., Bulut-Karslioglu A (2024). mTOR activity paces human blastocyst stage developmental progression. Cell Sep 18:S0092-8674(24)00977-2. doi: 10.1016/j.cell.2024.08.048
M. Ebisuya ,T. Rayon , M. Diaz-Cuadros , KJ. Chalut, G. Wu, AN. Dodd, ME. Torres-Padilla, M. Levine, VN. Gladyshev (2024). Understanding how cells and organisms keep time during development. Dev. Cell. Jun 15:S1534-5807(24)00363-0. doi: 10.1016/j.devcel.2024.05.029
C. Azzi, T. Rayon (2024). Timing mechanisms: insights from comparative neural differentiation systems. Curr Opin Genet Dev. Apr 21:86:102197. doi: 10.1016/j.gde.2024.102197.
S. Nakanoh*, K. Sham, S. Ghimire , I. Mohorianu*, T. Rayon*, L. Vallier* (2024). Human surface ectoderm and amniotic ectoderm are sequentially specified according to cellular density. Sci Adv. Mar;10(9):eadh7748. doi: 10.1126/sciadv.adh7748. *co-corresponding.
A. Libby^‡ and T. Rayon (2024)^‡. In preprints: puzzling together roles for glucose metabolism during gastrulation. Development 2024 Feb 15;151(4):dev202774. *co-corresponding.
D.P. Iyer, V.A. van der Weijden^‡, H.H. Khoei^‡, A. McCarthy, T. Rayon, C.S. Simon, I. Dunkel, S.E. Wamaitha, K. Elder, P. Snell, L. Christie, E.G. Schulz, K. Niakan, N. Rivron, A. Bulut-Karslioglu (2023). Delay of human early development via in vitro diapause. bioRxiv doi.org/10.1101/2023.05.29.541316. ^‡equal contribution.
T. Rayon (2023). Cell time: How cells control developmental timetables. Science Advances 9 (10): eadh1849.
T. Rayon* and J. Van den Ameele^*. (2022). In preprints: releasing the brakes on neuronal maturation. Development 149 (24): dev201477. *co-corresponding.

T. Rayon, R.J. Maizels, C. Barrington, and J. Briscoe. (2021). Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features. Development 148 (15):dev199711
T. Rayon, and J. Briscoe. (2021). Cross-species comparisons and in vitro models to study tempo in development and homeostasis. Interface Focus 11, rsfs.2020.0069.
T. Rayon*, D. Stamataki^‡, R. Perez-Carrasco^‡, L. Garcia-Perez, C. Barrington, M. Melchionda, K. Exelby, J. Lazaro, V. Tybulewicz, E. M. C. Fisher, J. Briscoe*. (2020). Species-specific developmental timing is associated with global differences in protein stability in mouse and human. Science 369, eaba7667. *co-corresponding author, ^‡equal contribution.
S. Menchero, I. Rollan, A. Lopez-Izquierdo, M. J. Andreu, J. Sainz de Aja, M. Kang, J. Adan, R. Benedito, T. Rayon, A.-K. Hadjantonakis, M. Manzanares. (2019). Transitions in cell potency during early mouse development are driven by Notch. eLife. 8 doi:10.7554/eLife.42930.
J. Delile^‡, T. Rayon, M. Melchionda, A. Edwards, J. Briscoe*, A. Sagner^‡*. (2019). Single cell transcriptomics reveals spatial and temporal dynamics of gene expression in the developing mouse spinal cord. Development 146 (12), dev173807. ^‡ Co-first authors, *co-corresponding author.
V. Metzis^‡, S. Steinhauser^‡, E. Pakanavicius, M. Gouti, D. Stamataki, K. Ivanovitch, T. Watson, T. Rayon, S. N. Mousavy Gharavy, R. Lovell-Badge, N. M. Luscombe, J. Briscoe. (2018). Nervous System Regionalization Entails Axial Allocation before Neural Differentiation. Cell 175, 1105-1118.e17 . ^‡Co-first authors.

T. Rayon^‡*, S. Menchero^‡, I. Rollán, I. Ors, A. Helness, M. Crespo, A. Nieto, V. Azuara, J. Rossant, M. Manzanares*. (2016). Distinct mechanisms regulate Cdx2 expression in the blastocyst and in trophoblast stem cells. Scientific Reports 6, 27139 . ^‡co-first authors,*co-corresponding author.
T. Rayon, S. Menchero, A. Nieto, P. Xenopoulos, M. Crespo, K. Cockburn, S. Cañon, H. Sasaki, A.-K. Hadjantonakis, J. L. de la Pompa, J. Rossant, M. Manzanares. (2014). Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. Developmental Cell 30, 410–22.
M. Abad, L. Mosteiro, C. Pantoja, M. Cañamero, T. Rayon, I. Ors, O. Graña, D. Megías, O. Domínguez, D. Martínez, M. Manzanares, S. Ortega, M. Serrano. (2013). Reprogramming in vivo produces teratomas and iPS cells with totipotency features. Nature 502, 340–5.